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In cases of renal colic, it is generally recommended to avoid using Ketorolac for pain management due to its potential impact on renal function. Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that can decrease renal perfusion and exacerbate kidney issues, particularly in patients who may already have compromised renal function due to the underlying cause of renal colic, such as kidney stones.

In contrast, the other options may be considered more favorable for pain relief in these situations. Ibuprofen, another NSAID, can be effective in managing pain but requires caution for the same reasons as Ketorolac, especially in high doses or with prolonged use. Acetaminophen is generally safer for renal function and can be used in moderation for pain relief, while Morphine, although an opioid, provides significant analgesic effects and can be utilized in manageable doses.

Therefore, recognizing the renal implications associated with Ketorolac is critical in the context of treating renal colic, making it a less suitable option for pain management in this scenario.