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The statement that naloxone is administered in cases of suspected opioid overdose is true because naloxone is specifically indicated for reversing the effects of opioid toxicity. It works as an opioid antagonist, meaning it binds to the same receptors in the brain as opioids but without producing the euphoric effects, effectively displacing the opioids and restoring normal respiratory function and consciousness in overdose situations.

In such emergencies, identifying signs of opioid overdose—like unresponsiveness, respiratory depression, and pinpoint pupils—supports the critical decision to use naloxone. It is an essential tool in prehospital care for paramedics when discerning cases of potential opioid overdose, as it plays a vital role in preventing fatal outcomes.

The other statements do not accurately reflect the use of naloxone in clinical practice. For instance, naloxone is not contraindicated in patients with uncontrolled hypertension, nor is it used for opioid-induced constipation. It also does not worsen symptoms of an overdose; rather, it is intended to alleviate the overdose effects.